目的 探讨妇乐颗粒联合左氧氟沙星和甲硝唑治疗急性盆腔炎的临床疗效。方法 选取2015年2月-2016年2月在屯昌县人民医院接受治疗的急性盆腔炎患者86例，按照治疗方法的差别分为对照组和治疗组，每组各43例。对照组患者静脉滴注盐酸左氧氟沙星氯化钠注射液，0.5 g/次，2次/d；并静脉滴注甲硝唑氯化钠注射，0.5 g/次，2次/d。治疗组在对照组基础上口服妇乐颗粒，2袋/次，2次/d。两组患者均治疗10 d。观察两组的临床疗效，比较两组的炎症因子、临床症状消失时间和临床症状评分情况。结果 治疗后，对照组和治疗组的总有效率分别为81.40%、95.35%，两组比较差异有统计学意义（P<0.05）。治疗后，两组hs-CRP、IL-6和TNF-α均显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组这些观察指标的降低程度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，治疗组体温降至正常时间、下腹痛消失时间和阴道分泌物增多的消失时间均短于对照组，两组比较差异有统计学意义（P<0.05）。治疗后，两组小腹疼痛、带下量多和腰骶胀痛评分均显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组这些观察指标的下降程度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。结论 妇乐颗粒联合左氧氟沙星和甲硝唑治疗急性盆腔炎具有较好的临床疗效，可改善临床症状，降低炎性症反应，具有一定的临床推广应用价值。

Objective To explore the clinical effect of Fule Granules combined with levofloxacin and metronidazole in treatment of acute pelvic inflammatory. Methods Patients (86 cases) with acute pelvic inflammatory in Tunchang County People's Hospital from February 2015 to February 2016 were enrolled in this study. According to the difference treatment plan, patients were randomly divided into control and treatment groups, and each group had 43 cases. Patients in the control group were iv administered with Levofloxacin Hydrochloride and Sodium Chloride Injection, 0.5 g/time, twice daily. And patients in the control group were also iv administered with Metronidazole and Sodium Chloride Injection, 0.5 g/time, twice daily. Patients in the treatment group were po administered with Fule Granules on the basis of the control group, 2 bags/time, twice daily. Patients in two groups were treated for 10 d. After treatment, the clinical efficacies were evaluated, and inflammatory factors, disappearance time of clinical symptoms, and clinical symptom scores in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 81.40% and 95.35%, respectively, and there was difference between two groups (P<0.05). After treatment, hs-CRP, IL-6, and TNF-α in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, the times of body temperature dropped to normal, lower abdominal pain disappeared time, and vaginal secretions increasing disappeared time in the treatment group were shorter than those in the control group, and there was difference between two groups (P<0.05). After treatment, the scores of lower abdomen pain, vaginal secretions increasing, and lumbosacral distending pain in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Fule Granules combined with levofloxacin and metronidazole has clinical curative effect in treatment of acute pelvic inflammatory, can improve clinical symptoms, and decreased inflammatory reaction, which has a certain clinical application value.