目的 探讨银杏蜜环口服溶液联合阿司匹林肠溶片和氯吡格雷治疗冠心病心绞痛的临床疗效。方法 选取2014年4月-2015年4月在西安市北方医院老年病科和心内科接受治疗的冠心病心绞痛患者120例，根据治疗方案的差别将上述患者分为对照组（60例）和治疗组（60例）。对照组患者口服阿司匹林肠溶片，100 mg/次，1次/d，首次剂量为300 mg；同时口服硫酸氢氯吡格雷片，75 mg/次，1次/d，首次剂量为300 mg。治疗组患者在对照组的基础上口服银杏蜜环口服溶液，10 mL/次，3次/d。两组患者均连续治疗两周。观察两组的临床疗效，同时比较两组症状和血液流变学指标改善情况。结果 治疗后，对照组和治疗组总有效率分别为86.67%和96.67%，两组比较差异具有统计学意义（P<0.05）。治疗后两组心绞痛发作次数、持续时间及缓解所需硝酸甘油用量较同组治疗前明显降低（P<0.05）；与对照组比较，治疗组症状改善情况优于对照组（P<0.05）。治疗后两组血浆黏度、血细胞比容（HCT）、纤维蛋白原（FIB）和血小板聚集率（MPA）均较同组治疗前明显降低，同组比较差异具有统计学意义（P<0.05）；且治疗组比对照组降低的更明显，差异具有统计学意义（P<0.05）。结论 银杏蜜环口服溶液联合阿司匹林肠溶片和氯吡格雷治疗冠心病心绞痛疗效显著，可明显改善患者临床症状，降低血液流变学指标，具有一定的临床推广应用价值。

Objective To observe the clinical curative effect of Ginkgo Leaf Extract and Armillariella Mellea Powders Oral Solution combined with Aspirin Enteric-coated Tablets and clopidogrel in treatment of coronary heart disease with angina pectoris. Methods Patients (120 cases) with coronary heart disease with angina pectoris in Department of Geratology and Cardiology of Xi'an North Hospital from April 2014 to April 2015were divided into control (60 cases) and treatment (60 cases) groups based on different treatments. Patients in the control group were po administered with Aspirin Enteric-coated Tablets, 100 mg/time, once daily, and the first dosage was 300 mg. And they were po administered with Clopidogrel Hydrogen Sulphate Tablets, 75 mg/time, once daily, the first dosage was 300 mg. The patients in the treatment group were po administered with Ginkgo Leaf Extract and Armillariella Mellea Powders Oral Solution on the basis of the control group, 10 mL/time, three times daily. The patients in two groups were treated for 2 weeks. After treatment, the clinical efficacy was evaluated, and the improvement of symptoms and hemorheology indexes in two groups were compared. Results After treatment, the efficacies in the control and treatment groups were 86.67% and 96.67%, respectively, and there were differences between two groups (P<0.05). After treatment, frequency and duration of angina pectoris, and also nitroglycerin dosage of two groups were significantly decreased (P<0.05). Compared with the control group, the improvement of symptoms in the treatment group was better than those in the control group (P<0.05). After treatment, MPA, FIB, plasma viscosity, and HCT in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the observational indexes in the treatment group were decreased more significantly than those in the control group, with significant difference between two groups (P<0.05). Conclusion Ginkgo Leaf Extract and Armillariella Mellea Powders Oral Solution combined with Aspirin Enteric-coated Tablets and clopidogrel has a clinical curative effect remarkable in treating of coronary heart disease with angina pectoris, can obviously improve the clinical symptoms and reduce the hemorheology indexes, which has a certain clinical application value.