目的 回顾分析北京医院外科住院病房2010-2015年万古霉素的用药情况，为临床合理使用万古霉素提供参考。方法 筛选北京医院2010年1月-2015年12月使用万古霉素的外科住院患者的全部病例，提取详细病例信息，并对各科室使用情况、药敏送检情况、临床有效率及用药合理性进行统计分析。结果 共筛选出病例454例，其中用药不合理89例（占19.6%），治疗有效的432例，有效率95.2%；万古霉素的总用药量4 263.3 g，总用药天数为3 307 d，限定日剂量（DDD）为2 g/d，药物利用指数（DUI）=0.64。结论 北京医院外科病房万古霉素使用基本合理，但仍有部分病例存在使用不规范情况。

Objective To analyze the usage of vancomycin in the surgical ward of Beijing Hospital during 2010-2015, so as to provide references for the rational use of vancomycin. Methods All hospitalized cases used vancomycin in Beijing Hospital from January 2010 to December 2015 were screened, and the detailed information was extracted. The usage of vancomycin in different departments, drug sensitive test, clinical efficiency percentage, and rationality of usage were then analyzed. Results A total of 454 cases were screened, of which 89 cases (19.6%) were unreasonable and 432 cases (95.2%) showed effective results; The total dosage of 4 263.3 g of vancomycin was used in 3 307 d, the DDD was 2 g/d, therefore, the DUI was 0.64. Conclusion The use of vancomycin in the surgical ward of Beijing Hospital is generally rational, however, some irrational cases are also found.