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[摘要]
目的 探讨卡前列甲酯栓联合酚妥拉明治疗产后尿潴留的临床疗效。方法 选取2014年7月-2015年7月武安市第一人民医院收治的产后尿潴留患者92例,按治疗方案的差别分为对照组和治疗组,每组各46例。对照组肌肉注射甲磺酸酚妥拉明注射液10 mg;治疗组在对照组基础上舌下含服卡前列甲酯栓1 mg,药物融化后缓慢吞咽,若60 min后仍排不出尿液者,重复上述治疗1次。观察两组的临床疗效,比较两组患者的尿潴留消失时间及住院时间。结果 治疗后,对照组和治疗组的总有效率分别为82.61%、95.65%,两组比较差异有统计学意义(P<0.05)。治疗后,治疗组患者的尿潴留消失时间及住院时间明显短于对照组,两组比较差异具有统计学意义(P<0.05)。结论 卡前列甲酯栓联合酚妥拉明治疗产后尿潴留具有较好的临床疗效,能缩短尿潴留消失时间以及住院时间,具有一定的临床推广应用价值。
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[Abstract]
Objective To explore the clinical effect of Carboprost Methylate Suppositories combined with phentolamine in treatment of postpartum urinary retention. Methods Patients (92 cases) with cerebral infarction in Wu'an First People's Hospital from July 2014 to July 2015 were enrolled in this study. According to the difference treatment plan, patients were divided into the control and treatment groups, and each group had 46 cases. Patients in the control group were im administered with Phentolamine Mesylate Injection, 10 mg. Patients in the treatment group were sublingual administered with Carboprost Methylate Suppositories on the basis of the control group, 1 mg, the drug was slowly swallowed after drug thawing, and the treatment was repeated for one time if urine cannot still be excreted after 60 min. After treatment, the clinical efficacies were evaluated, and the disappearance time of urinary retention and hospitalization time in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 82.61% and 95.65%, respectively, and there was difference between two groups (P<0.05). The disappearance time of urinary retention and hospitalization time in the treatment group were significantly shorter than those in the control group, with significant difference between two groups (P<0.05). Conclusion Carboprost Methylate Suppositories combined with phentolamine has the clinical curative effect in treatment of postpartum urinary retention, and can shorten the disappearance time of urinary retention and hospitalization time, which has a certain clinical application value.
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