目的 探讨妇科止血片联合米非司酮治疗更年期功能性子宫出血的临床疗效。方法 选取2013年4月-2015年2月在东明县人民医院妇产科进行治疗的更年期功能性子宫出血患者100例，随机分为对照组和治疗组，每组各50例。对照组患者口服米非司酮片，10 mg/次，1次/d，服用1个月后改为5 mg/次，1次/d，服用2个月。治疗组在对照组治疗基础上口服妇科止血灵片，5片/次，3次/d。两组均连续治疗3个月。观察两组的临床疗效，同时比较两组治疗前后促黄体生成素（LH）、卵泡刺激素（FSH）和孕酮（P）水平变化。结果 治疗后，对照组和治疗组的总有效率分别为80.0%、92.0%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者LH、FSH、P水平均显著降低，同组治疗前后差异有统计学意义（P<0.05）；治疗组这些激素水平的降低程度优于对照组，两组比较差异有统计学意义（P<0.05）。结论 妇科止血灵片联合米非司酮治疗更年期功能性出血具有较好的临床疗效，能显著降低LH、FSH、P水平，具有一定的临床推广应用价值。

Objective To investigate the clinical effects of Fuke Zhixueling Tablets combined with mifepristone in treatment of menopausal dysfunctional uterine bleeding. Methods Patients (100 cases) with menopausal dysfunctional uterine bleeding in Department of Obstetrics and Gynecology of People's Hospital of Dongming County from April 2013 to February 2015 were randomly divided into control (50 cases) and treatment (50 cases) groups. The patients in the control group were po administered with Mifepristone Tablets, 10 mg/time, once daily. After one month, the dosage was adjusted to 5 mg/time, once daily for 2 months. The patients in the treatment group were po administered with Fuke Zhixueling Tablets on the basis of the control group, 5 tablets/time, three times daily. The patients in two groups were treated for 3 months. After treatment, the clinical efficacies were evaluated, and the changes of LH, FSH, and P before and after treatment in two groups were compared. Results After treatment, the total efficacies in the control and treatment groups were 80.0% and 92.0%, respectively, and there were differences between two groups (P<0.05). The levels of LH, FSH, and P in two groups were decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the reduce degree of these hormone levels in the treatment group were better than those of control group, with significant difference between two groups (P<0.05). Conclusion Fuke Zhixueling Tablets combined with mifepristone has clinical curative effect in treatment of menopausal dysfunctional uterine bleeding, and can significantly reduce the levels of LH, FSH, P, which has a certain clinical application value.