目的 观察血必净注射液治疗儿童急性胰腺炎的临床疗效。方法 选取2013年1月—2015年9月哈励逊国际和平医院收治的儿童急性胰腺炎患者54例，所有患者随机分为对照组和治疗组，每组各27例。对照组采用常规治疗。治疗组在对照组的基础上静脉滴注血必净注射液0.5～1 mL/kg，加入0.9%氯化钠注射液50～10 mL，1次/d。两组患者均连续治疗10 d。观察两组的临床疗效，比较患者治疗前后临床体征和炎性因子的变化。结果 治疗后，对照组和治疗组总有效率分别为62.96%、81.48%，两组比较差异具有统计学意义（P<0.05）。治疗后，治疗组患者的临床体症消失时间、血淀粉酶恢复正常时间、正常饮食时间和住院时间均显著小于对照组，两组比较差异具有显著性（P<0.05）。治疗后，两组患者定C-反应蛋白（CRP）和降钙素原（PCT）均显著降低，同组治疗前后差异有统计学意义（P<0.05）；且治疗组这些观察指标的降低程度优于对照组，两组比较差异有统计学意义（P<0.05）。结论 血必净注射液治疗儿童急性胰腺炎具有较好的临床疗效，可改善临床体征，有效抑制炎性因子释放，安全性高，具有一定的临床推广应用价值。

Objective To observe the clinical efficacy of Xuebijing Injection in treatment of acute pancreatitis in Children. Methods Children (54 cases) with acute pancreatitis in Harrison International Peace Hospital from January 2013 to September 2015 were randomly divided into control group and treatment groups, and each group had 27 cases. Children in the control group were given routine treatment. Children in the treatment group were iv administered with Xuebijing Injection on the basis of control group, 0.5-1 mL/kg added into normal saline 50-100 mL, once daily. Children in two groups were treated for 10 d. After treatment, the efficacy was evaluated, and clinical symptoms and inflammatory factors between the two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 62.96% and 81.48%, respectively, and there was difference between two groups (P<0.05). After treatment, the disappeared time of clinical symptoms, serum amylase returned to normal time, return to normal diet time, and hospitalization time in the treatment group were significantly shorter than those in the control group, and there were differences between two groups (P<0.05). After the treatment, C-reactive protein (CRP) and procalcitonin (PCT) in two groups significantly decreased, and the differences were statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Xuebijing Injection has good clinical curative effect in treatment of acute pancreatitis in children, can further improve the clinical symptoms, significantly inhibit the release inflammatory factors in children with less adverse reactions, with a certain clinical application value.