目的 分析天津市宝坻区人民医院内分泌科住院患者抗菌药物的使用情况,为抗菌药物合理使用提供参考。方法 收集2013年1月-2014年12月天津市宝坻区人民医院内分泌科使用抗菌药物的住院患者374例,对患者的基本情况、感染分布、病原菌分布及其抗菌药物的使用情况进行分析。结果 374例抗菌药物使用患者中,女性多于男性,且年龄多集中于61岁以上,患者以2型糖尿病及其相关并发症为主,感染部位主要集中在泌尿系和呼吸道,病原菌以革兰阴性菌为主。单独使用1种抗菌药物的比例相对较高,头孢菌素类使用品种、例次最多,DDDs排序前10位的抗菌药物中只有左氧氟沙星为口服给药,其他均为静脉滴注,头孢哌酮钠舒巴坦钠的DDDs位列第1位。结论 天津市宝坻区人民医院内分泌科住院患者抗菌药物的临床应用相对合理。

Objective To analyze the utilization of antibacterial drugs for inpatients in Department of Endocrinology of Tianjin Baodi People's Hospital, and to provide reference for rational application of antibiotics. Methods The inpatients (374 cases) using antibiotics in Department of Endocrinology of Tianjin Baodi People's Hospital from January 2013 to December 2014 were collected. The basic information of patients, distribution of infection, distribution of main pathogenic bacteria, and utilization of antibacterial drugs were analyzed. Results In the inpatients (374 cases) using antibiotics, female were more than male, and the ages of patients were mainly above 61 years old. Most patients were ill with type 2 diabetes and related complications. Infection site were concentrated in urinary tract and respiratory tract. Gram-negative bacteria were the main pathogenic bacteria. Most of patients used one kind of antibiotics. The most variety and case time of using was cephalosporins. Only levofloxacin in top 10 antibiotics in the list of DDDs was orally given, while others were given with iv drip. DDDs of cefoperazone sodium sulbactam sodium was ranked the first. Conclusion The clinical application of antibiotics in Department of Endocrinology of Tianjin Baodi People's Hospital is relatively reasonable.