姜黄素是姜黄的主要活性成分,应用于各种疾病领域。研究表明,姜黄素对多个系统相关癌症都具有保护效应。其分子作用机制是通过抑制多个水平细胞的信号传导途径实现的。姜黄素通过与目标分子形成黏合物直接或间接地抑制其细胞的致癌性,这些目标分子包括转录因子、生长因子、酶、激酶、活性细胞激素、浆液、抗性蛋白。主要阐明了姜黄素对泌尿生殖系统癌症的抗癌疗效,以及其分子传导途径,为其在癌症治疗中更广泛的应用提供参考。

Curcumin is the main active component of Curcuma longa L., and has been used in treatment of various diseases. Studies have indicated that curcumin has protective effects on multiple organ systems. The molecular mechanism is achieved by inhibiting the signal transduction pathway of multiple levels of cells. Curcumin can inhibit the cell's activity directly or indirectly by the formation of the target molecules. These target molecules include transcription factors, growth factors, enzymes, proteins, enzymes, active cells, serum, and resistance proteins. In this paper, the effects of curcumin on the cancer of the urinary and reproductive systems, and their molecular pathways, which provide a reference for more extensive application in treatment of various carcinomas.