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[摘要]
目的 研究龙金通淋胶囊联合左氧氟沙星治疗Ⅲ型前列腺炎的疗效,为临床上Ⅲ型前列腺炎的药物治疗提供依据。方法 选择2013年10月—2015年6月天津中医药大学第一附属医院泌尿外科收治的Ⅲ型前列腺炎患者80例,随机分为对照组和治疗组,每组各40例。对照组患者口服盐酸左氧氟沙星片,0.2 g/次,2次/d。治疗组在对照组治疗基础上口服龙金通淋胶囊,3粒/次,3次/d。两组均连续治疗8周。观察两组的临床疗效,同时比较两组慢性前列腺炎症状指数(NIH-CPSI)评分、前列腺液白细胞数的变化情况。结果 治疗后,对照组和治疗组的总有效率分别为62.5%、87.5%,两组比较差异有统计学意义(P<0.05)。治疗后,两组前列腺液白细胞数、疼痛评分、排尿症状评分、生活质量影响评分和NIH-CPSI总评分均较治疗前显著降低,同组治疗前后差异具有统计学意义(P<0.05);且治疗后,治疗组这些观察指标显著低于对照组,两组比较差异具有统计学意义(P<0.05)。结论 龙金通淋胶囊联合左氧氟沙星治疗Ⅲ型前列腺炎具有较好的临床疗效,可改善患者的NIH-CPSI评分,降低前列腺液白细胞数目,具有一定的临床推广应用价值。
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[Abstract]
Objective To explore the clinical effect of Longjin Tonglin Capsules combined with levofloxacin in treatment of type III prostatitis, to provide clinical basis of drug treatment for Ⅲ Type of prostatitis. Methods Patients (80 cases) with type III prostatitis in Department of Urological Surgery of First Teaching Hospital of Tianjin University of TCM from October 2013 to June 2015 were randomly divided into control and treatment groups, and each group had 40 cases. The patients in the control group were po administered with Levofloxacin Hydrochloride Tablets, 0.2 g/time, twice daily. The patients in the treatment group were po administered with Longjin Tonglin Capsules on the basis of control group, 3 grains/time, three times daily. The patients in two groups were treated for eight weeks. After treatment, the clinical efficacies were evaluated, and the changes of NIH-CPSI scores and leukocyte number of prostate fluid in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 62.5% and 87.5%, respectively, and there were differences between two groups (P< 0.05). After treatment, leukocyte number of prostate fluid, pain score, urination symptom score, quality of life score, and NI-CPSI total score in two groups were significantly decreased, and the difference was statistically significant in the same group (P< 0.05). After treatment, the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P< 0.05). Conclusion Longjin Tonglin Capsules combined with levofloxacin has clinical curative effect in treatment of type III prostatitis, and can improve the NIH-CPSI score, also can reduce the leukocyte number of prostate fluid, which has a certain clinical application value.
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