目的 了解辽宁省肿瘤医院麻醉药品的应用现状及变化趋势,为临床合理用药提供参考。方法 收集辽宁省肿瘤医院2013—2014年麻醉药品的应用数据,对其用量、销售金额、用药频度(DDDs)、日均药费(DDC)及药品排序比(B/A)等进行统计和分析。结果 2013—2014年用量排前两位的为磷酸可待因片和盐酸羟考酮缓释片(10 mg);芬太尼透皮贴剂(8.4 mg)与盐酸羟考酮缓释片(40 mg)位列销售金额的前两位。芬太尼透皮贴剂(40 mg)与枸橼酸芬太尼注射液的DDDs始终保持在前两位,但有下降的趋势。枸橼酸舒芬太尼注射液、注射用盐酸瑞芬太尼、盐酸羟考酮缓释片(10 mg)的DDC居前3位。B/A接近1的药品包括芬太尼透皮贴剂、盐酸吗啡注射液、盐酸吗啡片、盐酸哌替啶注射液、阿片片。结论 辽宁省肿瘤医院麻醉药品的应用基本合理。

Objective To investigate the usage and variation tendency of narcotic drugs in Liaoning Cancer Hospital and Institute, and to provide reference for rational drug use in clinic. Methods The data of narcotic drugs in Liaoning Cancer Hospital and Institute from 2013 to 2014 were collected, and the consumption quantity, consumption sum, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) were calculated and analyzed. Results During 2013—2014, the top two consumption quantity of narcotic drugs were Codeine Phosphate Tablets and Oxycodone Hydrochloride Prolonged-release Tablets (10 mg). Consumption sum of Fentanyl Transdermal Patches (8.4 mg) and Oxycodone Hydrochloride Prolonged-release Tablets (40 mg) ranked the top two. DDDs of Fentanyl Transdermal Patches (40 mg) and Fentanyl Citrate Injection ranked the first two persistently, but they had a tendency to decline. DDC of Sufentanil Citrate Injection, Remifentanil Hydrochloride for injection, and Oxycodone Hydrochloride Prolonged-release Tablets (10 mg) ranked the top three. The narcotic drugs whose B/A was close to 1 included Sufentanil Citrate Injection, Morphine Hydrochloride Injection, Morphine Hydrochloride Tablets, Pethidine Hydrochloride Injection, and Opium Tablets. Conclusion The utilization of narcotic drugs in Liaoning Cancer Hospital and Institute is basically reasonable.