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[摘要]
目的 分析上海市浦东新区周浦医院门急诊口服非甾体抗炎药(NSAIDs)的使用情况,为临床合理用药提供参考。方法 对上海市浦东新区周浦医院2012—2014年门急诊的口服非甾体抗炎药的用药金额、用药频度(DDDs)、限定日费用(DDC)及药品排序比(B/A)等进行统计和分析。结果 非甾体抗炎药的用药金额在2014年迅速增长;阿司匹林肠溶片、洛索洛芬钠胶囊和美洛昔康分散片的DDDs一直稳居前3位;塞来昔布胶囊的DDC在所有非甾体抗炎药中最高。B/A>1.5的有酚氨咖敏片、阿司匹林肠溶片和安乃近片,B/A<0.7的有塞来昔布胶囊、洛索洛芬钠片、奥沙普秦肠溶片和氨麻美敏片Ⅱ。结论 上海市浦东新区周浦医院的非甾体抗炎药的使用基本合理,正朝着长效和低毒的新剂型方向发展。
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[Abstract]
Objective To analyze the utilization of oral nonsteroidal anti-inflammatory drugs (NSAIDs) in Department of Outpatient and Emergency of Shanghai Pudong New District Zhoupu Hospital, so as to provide reference for rational use in clinic. Methods Consumption sum, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) of NSAIDs in Department of Outpatient and Emergency of Shanghai Pudong New District Zhoupu Hospital from 2012 to 2014 were calculated and analyzed. Results Consumption sum of oral NSAIDs in 2014 increased rapidly. DDDs of Aspirin Enteric-coated Tablets, Loxoprofen Sodium Capsules, and Meloxicam Dispersible Tablets ranked the first three persistently. DDC of Celecoxib Capsules was the highest in all NSAIDs. NSAIDs whose B/A were above 1.5 included Fen'ankamin Tablets, Aspirin Enteric-coated Tablets, and Metamizole Sodium Tablets. NSAIDs whose B/A were below 0.7 included Celecoxib Capsules, Loxoprofen Sodium Tablets, Oxaprozin Enteric-coated Tablets, and Compound Dextromethorphan Hydrobromide Tablets Ⅱ. Conclusion The utilization of NSAIDs in Shanghai Pudong New District Zhoupu Hospital is generally rational, and is developing toward the direction of new dosage forms with long-term and low toxicity.
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