目的 研究2011—2013年常熟市第一人民医院抗菌药物的使用情况和发展趋势,为规范合理用药提供参考.方法 选取2011—2013年使用抗菌药物治疗的患者648例进行回顾性分析,分别从抗菌药物科室分布、使用品种、联合用药、销售金额、使用频度(DDDs)、限定日费用(DDDc)等方面进行统计分析,对抗菌药物使用的基本情况进行汇总分析.结果 在调查的648例病例中,ICU患者抗菌药物使用所占比例最高,同时治疗类药物的使用大于预防类药物.抗菌药物联用情况明显,占到总数的20%左右,单独使用一种抗菌药物时,药物多为一线药物,价格较高.2011—2013年头孢类药物的销售金额、DDDs、DDDc均排在最前面,表明头孢类药物使用率高.结论 2011—2013年常熟市第一人民医院抗菌药物的使用基本合理,但有部分科室、部分药物使用情况不合理,还需进一步加强管理.

Objective To study the utilization and trends of antimicrobial drugs in Changshu No. 1 People's Hospital from 2011 to 2013, and to provide a reference for standardizing the rational use of drugs. Methods The utilization of antimicrobial drugs to patients (648 cases) was summarized retrospectively, and department distribution, varieties, drug combination, consumption sum, frequency of drug use (DDDs), and defined daily cost (DDDc) were analyzed statistically. Results In 648 patients, there were the most patients using antimicrobial drugs in ICU. And antimicrobial drugs for treatment were used more than those for prevention. Drug combination was quite common, accounting for about 20%. Most of the single medication were first-line and expensive drugs. Consumption sum, DDDs, and DDDc of cephalosporins ranked the first during 2011—2013, indicating that the utilization rate of cephalosporins was high. Conclusion The utilization of antimicrobial drugs is basically rational in Changshu No. 1 People's Hospital during 2011—2013, but there is also some unreasonable medication in some departments and some antimicrobial drugs, which needs further efforts to strengthen the management.