目的 调查天津市中心妇产科医院2013年住院患者抗菌药物的使用情况,并分析评估其使用合理性.方法 采用回顾性调查方法对随机选取的360份病历中抗菌药物的使用情况进行汇总,分别从抗菌药物使用品种、费用、科室分布、联合用药等方面进行统计分析.结果 360例病历中155份使用了抗菌药物,抗菌药物的使用率为43.06%,其中产科使用例数为67例,使用率(77.91%)最高,联合用药比例为18.07%,62份病历为不合理用药,占17.22%.结论 天津市中心妇产科医院抗菌药物使用基本合理,但少数病历存在用药不合理现象.抗菌药物的管理需要多部门共同参与,医师应严格用药指征,临床药师应加强培训,医院加强监督管理.

Objective To investigate the utilization of antimicrobials of in-patients in Tianjin Central Hospital of Gynecology Obstetrics in 2013, and evaluate its rationality. Methods The utilization of antimicrobials to in-patients (360 cases) was summarized retrospectively, and the varieties, costs, department distribution, and drug combination were analyzed statistically. Results In 360 cases of in-patients, 155 cases used antimicrobials. The utilization ratio of antimicrobials was 43.06%. There were 67 cases using antimicrobials in obstetrics. The utilization ratio of antimicrobials was the highest (77.91%). The utilization ratio of patients who used combined drugs was 18.07%. Sixty-two cases were unreasonable (17.22%). Conclusion The utilization of antimicrobials is basically reasonable in Tianjin Central Hospital of Gynecology Obstetrics, but there are still some unreasonable use of antimicrobials. Multi-departments need to participate in the management of antimicrobials together. Physicians should be strict to the medication indications and clinical pharmacists should receive the more and better training, and the hospital should strengthen supervision.