目的 观察消脂胶囊联合非诺贝特治疗高脂血症的临床疗效。方法 将2012年12月-2013年12月于天津市中医药研究院附属医院就诊的高脂血症患者60例，随机分为对照组和治疗组，每组各30例。对照组口服非诺贝特片200 mg，1次/d；治疗组在对照组的基础上口服消脂胶囊3粒，3次/d。两组患者均服药持续性治疗8周。治疗结束后，观察两组患者临床疗效、中医证候疗效以及血脂指标变化。结果 治疗后治疗组的临床疗效、中医证候疗效、血脂指标变化与对照组比较差异均有统计学意义（P<0.05）。结论 消脂胶囊联合非诺贝特治疗高脂血症有较好的临床疗效，值得临床推广应用。

Objective To observe the clinical efficacy of Xiaozhi Capsules combined with fenofibrate in the treatment of hyperlipidemia. Methods Patients with hyperlipidemia (60 cases) who came to Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital from December 2012 to December 2013 for treatment were randomly divided into treatment and control groups (30 cases in each group). The patients in the control group were po administered with Fenofibrate Tablets (200 mg), once daily. On the basis of the control group, the patients in the treatment group were po administered with Xiaozhi Capsules (three grains), three times daily. Two patients were treated continuously for 8 weeks. After treatment, the clinical efficacy, syndrome curative efficacy of traditional Chinese medicine, and blood lipid indexes in two groups were observed. Results After treatment, the clinical curative effect, syndrome curative efficacy of traditional Chinese medicine, and blood lipid indexes had statistically differences, compared with those of the control group (P < 0.05). Conclusion Xiaozhi Capsules combined with fenofibrate has the remarkable clinical efficacy in the treatment of hyperlipidemia, which is worth of clinic application.

天津市卫生局中医、中西医结合科研课题（07033）