目的 观察炔雌醇环丙孕酮片与散结镇痛胶囊联合治疗子宫腺肌病的临床疗效。方法 选取2013年l-6月天津市静海县医院收治的伴有不同程度痛经的子宫腺肌病患者60例，随机分为治疗组和对照组，各30例。两组均于月经来潮第5天开始服用炔雌醇环丙孕酮片，1片/d，连续服用21 d，治疗组于月经第1天时加服散结镇痛胶囊，1.6 g/次，3次/d，连续3～6个月。随访6个月，随访内容包括痛经情况、月经量、子宫体积及CA12-5水平等。结果 对照组总有效率为86.67%，治疗组为96.77%，两组总有效率比较差异具有统计学意义（P<0.05）。治疗6个月后，两组患者痛经情况、月经量、子宫体积及CA12-5水平均较治疗前明显改善（P<0.05），但治疗组改善情况均优于对照组，差异具有统计学意义（P<0.05）。治疗过程中未出现明显不良反应。结论 炔雌醇环丙孕酮片联合散结镇痛胶囊治疗子宫腺肌病具有较好的临床疗效。

Objective To observe the therapeutic effect of Ethinylestradiol and Cyproterone Acetate Tablets combined with Sanjie Zhentong Capsules in the treatment of adenomyosis. Methods Patients (60 cases) with myopathy associated with different degrees of dysmenorrhea in adenomyosis, who came to Hospital of Jinghai County of Tianjin City for the treatment from January to June 2013, were randomly divided into treatment and control groups (30 cases in each group). Patients in the both groups took Ethinylestradiol and Cyproterone Acetate Tablets 1 tablet daily, for 21 d from day 5 of menstruation. On the basis of conventional therapy, the patients in the treatment group took Sanjie Zhentong Capsules 1.6 g once, three times daily, for 3-6 months on day 1 of menstruation. The patients were followed up for 6 months including dysmenorrhea, menstrual quantity, uterus volume, and CA12-5 level. Results The total effective rate for the patients in the control group was 86.67%, the treatment group was 96.77%, and the difference between the two groups was statistically significant (P< 0.05). After the treatment for 6 months, dysmenorrhea, menstrual quantity, uterus volume and CA12-5 level were significantly improved compared with the same group before the treatment (P< 0.05), and efficacy in the treatment group was significantly better than that in the control group (P< 0.05).There were not obvious adverse reactions during the treatment. Conclusion Ethinylestradiol and Cyproterone Acetate Tablets combined with Sanjie Zhentong Capsule in the treatment of adenomyosis have good clinical effect.