目的 建立复方金钱草颗粒的质量控制方法，为其质量控制提供依据。方法 采用薄层色谱法对复方金钱草颗粒处方中广金钱草、光石韦药材进行定性鉴别，采用高效液相色谱法测定复方金钱草颗粒中芒果苷。结果 确定了处方中广金钱草、光石韦的薄层色谱鉴别方法，在选定的薄层色谱条件下，色谱斑点分离较好，阴性无干扰。芒果苷进样量在0.060 5～0.605 0 μg与峰面积呈良好的线性关系（r=0.999 5），平均回收率为99.52%，RSD值为2.13%。结论 所建立的方法简便、准确、专属性强、重复性好，可有效地控制复方金钱草颗粒的质量。

Objective To establish a quality standard of Compound Jinqiancao Granules for scientific evaluation and effective control of its quality to provide a reliable basis. Methods The herbs in the formula, such as Desmodii Styracifolii Herba and Pyrrosiae Folium were identified by TLC. Contents of mangiferin were determined by HPLC method. Results The method was established to distinguish Desmodii Styracifolii Herba and Pyrrosiae Folium. The spots in the TLC chromatograms were clear, and there were no interference from negative control. Mangiferin had a good linearity in the range of 0.060 5 — 0.605 0 μg (r=0.999 5). The average recovery was 99.52%, and RSD value was 2.13%. Conclusion The method is simple and accurate, and has a good reproducibility, which can be used for the quality control of Compound Jinqiancao Granules.

广西科技攻关项目（桂科攻1099062-4；桂科转13109005；桂科转13129006）