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[摘要]
目的 探讨七氟醚复合罗库溴铵全麻对剖宫产的有效性和安全性。方法 选择需要择期于全身麻醉下行剖官产术的产妇30例为全麻组,随机选取同期硬膜外麻醉下择期剖宫产的产妇30例为对照组。全麻组采用七氟醚复合罗库溴铵进行诱导麻醉。对照组采用0.75%罗哌卡因进行椎管内麻醉。比较两组产妇平均动脉压(MAP)、血氧饱和度(SpO2)、心率(HR)的情况,并记录胎儿娩出1、5 min时新生儿Apgar评分。结果 全麻组产妇在手术切皮和胎儿娩出时MAP、HR较对照组高,两组比较差异有统计学意义(P<0.05);其余观察时间两组患者MAP、SpO2、HR比较差异均无统计学意义。两组新生儿出生1、5min均无窒息情况发生,Apgar评分均在9分以上,新生儿娩出1、5 min时两组Apgar评分比较差异无统计学意义。结论 七氟醚复合罗库溴铵全麻对剖宫产的效果较好,对患者血流动力学的影响较轻微,新生儿Apgar评分满意,是剖宫产需全麻时比较安全的选择。
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[Abstract]
Objective To investigate the efficacy and safety of general anesthesia induced by sevoflurane combined with rocuronium in the cesarean delivery. Methods Pregnant women undergone elective cesarean section with general anesthesia (30 cases) were as general anesthesia group. of pregnant women undergone epidural anesthesia (30 cases) were randomly selected to be the control group. Pregnant women in general anesthesia group were induced with sevoflurane and rocuronium. In the control group, the pregnant women were administered by spinal canal anesthesia with ropivacaine. MAP, SpO2, and HR of two groups were compared. Apgar scores of two groups were recorded after 1 and 5 min the children birthed. Results MAP and HR of the patients in general anesthesia group were obviously higher than those in the control group when the skin was cut and children birthed (P < 0.05). There was no difference in MAP, SpO2, and HR in the rest of the observation time between two groups. The newborn had no asphyxia after 1 and 5 min they birthed. Apgar scores were above 9 point, and there were no statistical significance between two groups. Conclusion Sevoflurane combined with rocuronium has an good effect on cesarean delivery, which can provide lesser impact on hemodynamics of pregnant women, and Apgar scores of newborn are satisfactory. It is a relatively safer choice for cesarean section.
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