With the increasingly widespread use of Chinese materia medica (CMM) injection, the adverse drug reactions (ADR) are paid more and more attention. To avoid possible ADR occuring, it is important that the pharmaceutical care of clinical pharmacists should be done in CMM injections. The pharmaceutical care plays an important role in the application of CMM injections safely, effectively, and reasonably. The most important things of pharmaceutical care of CMM injections are as follows: according to the principle of treatment based on syndrome differentiation in clinical application, the dialectical application of CMM injections; selecting the correct solvent; avoiding drug incompatibility; controlling the transfusion speed; no treatment with overdose of CMM injections in order to achieve the disease lasts. Recently, the pharmaceutical care has achieved more and more development in the clinical application of CMM injections.