目的 研究输液相关不良事件与给药剂量因素间的相关性，确证影响输液相关不良事件的主要因素，以期减少输液相关不良事件的发生率。方法 以前瞻性及回顾性的队列研究方法对输液相关不良事件与给药剂量因素的相关性进行研究。根据照纳入及排除标准筛选研究对象，接受输液治疗的患者中暴露于某一研究因素的为暴露组，未暴露于这一因素的为非暴露组。观察两组中不良反应（ADRs）的发生情况。利用SPSS 15.0软件对研究数据进行χ2检验。分析两组间ADRs发生率及计算相对危险度（RR）。结果 两组输液不良反应发生率有明显差异（P＜0.05）。结论 给药剂量合理性与输液不良反应发生率相关。

Objective To study the correlation between the adverse transfusion reactions and the dosage factor, to corroborate the main factors related to the adverse transfusion reactions, and to decrease the incidence of adverse transfusion reactions. Methods A prospective and retrospective cohort study method was used to study the correlation between adverse transfusion reactions and dosage factors including dripping rate and dosage. The patients were screened and grouped according to inclusive and exclusive criteria. Among the patients with transfusion treatment, those exposed to some research factors were grouped in exposure group, while those not exposed to the same research factor were grouped in non-exposed group. The incidence of adverse transfusion reactions was observed. The data were analyzed with χ2 test method which could be performed by SPSS 15.0 software. The incidence of adverse transfusion reactions in two groups and the relative risk were analyzed. Results There were significant differences between the rationality of dosage factor and the incidences of adverse events (P < 0.05). Conclusion The rationality of dosage factor was correlated with the rate of adverse transfusion reactions.