白芍是毛茛科植物芍药的干燥根，含有多种具有生理活性的化学成分。白芍总苷（TGP）是从白芍中提取的一组糖苷类物质的总称，此糖苷类物质包括芍药苷、芍药花苷、羟基芍药苷、苯甲酰芍药苷、芍药内酯苷等，其中芍药苷和芍药内酯苷是其主要成分。药理及临床研究发现TGP具有抗炎、调节免疫、镇痛等功效，近年来TGP已被广泛应用于多种肾脏疾病的临床治疗。就TGP治疗肾脏疾病的药理作用及临床应用研究进展做一综述。

Paeoniae Radix Alba is the dried roots of Paeonia lactiflora in Ranunculaceae, which contains a variety of chemical composition with physiological effects. Total glucoside from Paeoniae Radix Alba (TGP) is a general term for a group of glycosides substances which is extracted from Paeoniae Radix Alba. The TGP includes paeoniflorin, peony flower glucoside, hydroxy paeoniflorin, benzoyl paeoniflorin, peony lactone glycosides, and so on. The main compositions are paeoniflorin and peony lactone glycosides. Pharmacological and clinical researches find that TGP has anti-inflammatory, immunomodulatory, and analgesic functions. It has been widely applied in a variety of clinical treatment of kidney disease in recent years. This article makes a summary on the the research progress in pharmacological effects and clinical application of TGP in the treatment of kidney diseases.