目的 优选仙慈丹处方药材的提取工艺。方法 以干浸膏得率和野黄芩苷的保留率为评价指标，高效液相色谱法定量，采用L9(34)正交试验对仙慈丹水提取工艺进行优化。结果 仙慈丹的最佳提取工艺为：水回流提取3次，每次0.5 h，溶媒倍量分别为12、10、10倍。结论 该提取工艺参数稳定、可行，适用于仙慈丹处方药材的提取。

Objective To optimize the extract process for Xiancidan prescription. Methods Dry extract yield and the retention rates of scutellarin were used as indexes, HPLC was used to quantify, and the effects of extraction time, the amount of water, extracting times, and degree on extraction technology were evaluated by L9(34) orthogonal test. Results The optimum technical parameters of the water extracting technology were as follows: circumfluence extracting for 3 times with 12, 10, and 10 times the amount of water, 0.5 h per time. Conclusion The preparation procedure is stable and feasible and it can be used for the extraction of Xiancidan prescription.

广东省科技计划项目（2010B030700001）