目的 建立龙血竭的5种成分定量分析方法，为科学评价和有效控制龙血竭的质量提供依据。方法 采用Phenomenex Kinetex C18柱（100 mm×4.6 mm，2.6 μm），以乙腈–水梯度洗脱，体积流量：1.7 mL/min，柱温：40 ℃，检测波长为280 nm和325 nm。结果 白藜芦醇、7,4′-二羟基黄酮、龙血素A、龙血素B和紫檀茋分别在7.76～248.4 μg/mL（r=0.999 9）、6.84～219 μg/mL（r=1.000 0）、5.75～184 μg/mL（r=1.000 0）、10.08～322.6 μg/mL（r=1.000 0）和23.71～758.6 μg/mL（r=0.999 8）呈良好的线性关系，平均回收率分别为97.61%、99.24%、102.72%、101.75%、102.65%，RSD值分别为1.16%、0.87%、0.86%、0.49%、1.10%。结论 本方法快速、简便、准确，其结果可为龙血竭质量标准的制定提供一定的依据。

Objective To establish a quantitative analysis method for the determination of multi-components in Draconis Resina, and to provide a evidence for the scientific evaluation and effective quality control of Draconis Resina. Methods Phenomenex Kinetex C18 column (100 mm × 4.6 mm, 2.6 μm) was used with a mobile phase of acetonitrile-water gradient elution. The flow rate was 1.7 mL/min, the column temperature was 40 ℃, and the detection wavelengths were 280 and 325 nm. Results The linear ranges of resveratrol, 7,4′-dihydroxy flavone, loureirin A, loureirin B, and pterostilbene were 7.76—248.4 μg/mL (r = 0.999 9), 6.84—219 μg/mL (r = 1.000 0), 5.75—184 μg/mL (r = 1.000 0), 0.08—322.6 μg/mL (r = 1.000 0), and 23.71—758.6 μg/mL (r = 0.999 8), respectively. The average recoveries of the five components were 97.61%, 99.24%, 102.72%, 101.75%, and 102.65% with RSD values of 1.16%, 0.87%, 0.86%, 0.49%, and 1.10%. Conclusion The method is rapid, simple, and accurate, and could be used for the quality control of Draconis Resina.