目的 优选夏黄颗粒处方药材的乙醇提取工艺条件。方法 以乙醇体积分数、乙醇用量、提取时间、提取次数为考察因素，采用L9(34)正交试验设计，对5种蒽醌总转移率、出膏率两个指标进行综合评分，优选出最佳工艺。结果 最佳提取工艺为10倍量60%乙醇回流提取2次，每次1.5 h。结论 优选出的夏黄颗粒处方药材的最佳工艺合理，经验证其稳定可行，有效成分提取率较高。

Objective To optimize the ethanol extraction process for medicinal materials in Xiahuang Granule prescription. Methods Taking the concentration of ethanol, extraction time, amount of ethanol, and extraction times as factors, L9(34) orthogonal test was designed and evaluated with multi-index of yiled and powdered extract yield of five anthraquinones. Results The optimal extraction technology was as follows: reflux extracted twice with 10 times the amount of 60% ethanol, for 1.5 h once. Conclusion This optimized extraction technology is feasible, stable, and reasonable with high yield of active ingredients.