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[摘要]
目的 研究葛根正丁醇萃取物的化学成分。方法 采用聚酰胺柱色谱、反相ODS柱色谱、凝胶柱色谱、制备液相色谱等方法进行分离纯化,根据化合物的理化性质及波谱数据鉴定其结构。结果 分离鉴定了12个化合物,分别为葛酚苷元A(1)、葛酚苷元B(2)、染料木素(3)、3′-甲氧基葛根素(4)、3′-羟基葛根素(5)、葛根素芹糖苷(6)、葛根素木糖苷(7)、大豆苷元(8)、大豆素7,4′-二葡萄糖苷(9)、大豆苷(10)、葛根素(11)、胡萝卜苷(12)。结论 其中化合物1、2为首次从葛属植物中分离得到。
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[Abstract]
Objective To study the chemical constituents in n-buytl alcohol fraction of Puerariae Radix. Methods The compounds were isolated by Polyamide, ODS, and Sephadex LH-20 column chromatographies, and preparative HPLC, and their structures were identified by spectral analyses and physiochemical properties. Results Twelve compounds were isolated and identified as puerol A (1), puerol B (2), genistein (3), 3′-methoxy puerarin (4), 3′-hydroxyl puerarin (5), mirificin (6), puerarin xylosidde (7), daidzein (8), daidzein 7,4′-diglucoside (9), daidzin (10), puerarin (11), and daucosterol (12). Conclusion Compouds 1—2 are isolated from the plants of Pueraria DC. for the first time.
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