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[摘要]
目的 研究金银忍冬叶Lonicera macckii (Rupr.) Maxim.的化学成分。方法 采用硅胶柱色谱、Sephadex LH-2柱色谱、重结晶等方法进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果 从金银忍冬叶中分离鉴定了12个化合物,分别为山柰酚(1)、芹菜素(2)、金丝桃苷(3)、芹菜素-7-O-β-D-吡喃葡萄糖苷(4)、金圣草素-4′-O-β-D-葡萄糖苷(5)、木犀草素-7-O-β-D-吡喃葡萄糖苷(6)、裂环马钱素酸(7)、獐牙菜苷(8)、3,5-O-二咖啡酰基奎宁酸甲酯(9)、齐墩果酸(10),胡萝卜苷(11)、β-谷甾醇(12)。结论 化合物1~6、8~12为首次从该植物中分离得到,化合物5为首次从该属植物中分离得到。
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[Abstract]
Objective To study the chemical constituents from the leaves of Lonicera macckii. Methods The compounds were isolated and purified gel column chromatography, Sephadex LH-2 column chromatography and recrystallization, and their structures were identified by spectral analyses and physiochemical properties. Results Twelve compounds were isolated and identified as kaempferol (1), apigenin (2), hyperoside (3), apigenin-7-O-β-D-glucopyranoside (4), chrysoeri-ol-4′-O-β-D-glucopyranoside (5), luteolin-7-O-β-D-glucopyranoside (6), secologanin acid (7), sweroside (8), methyl 3,5-O-dicaffeoylquinate (9), oleanolic acid (10), β-sitosterol (11), and daucosterol (12), respectively. Conclusion Compounds 1—6 and 8—12 are isolated from this plant for the first time, and compound 5 is isolated from this genus for the first time.
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