目的 观察注射用红花黄色素在老年患者脑梗死恢复期早期的治疗疗效。方法 老年脑梗死恢复期早期患者（病后1～3个月）44例，随机分为治疗组和对照组各22例，治疗组用注射用红花黄色素100 mg，对照组用盐酸川芎嗪注射液80 mg，分别加入生理盐水250 mL中静滴，1次/d，治疗14 d，治疗前后患者进行临床疗效评分及经颅多普勒超声（TCD）检查并记录大脑前动脉、中动脉动脉收缩期最大血流速度（Vsp）及平均血流速度（Vmv）。同时，观察治疗过程中两组患者有无不良反应发生。结果 治疗后，治疗组疗效评分总有效率59.09%，对照组为45.45%，两组疗效差异有显著性（P＜0.05）。TCD检查治疗组患者责任病灶和非责任病灶侧大脑中动脉Vsp及Vmv增加较对照组更为明显（P＜0.01，P＜0.05）。两组患者均未出现严重的不良反应。结论 注射用红花黄色素能通过改善患者非责任病灶侧血管的血流而改善临床症状，在脑梗死恢复期早期可适当选用，同时无不良反应发生。

Objective To observe the effect of safflower yellow for injection in treatment of elderly patients with cerebral infarction at early recovery stage. Methods Elderly patients (44 cases) with cerebral infarction at early recovery stage (suffered from the disease for 1—3 month) were randomly divided into the treatment (22 cases) and control (22 cases) groups. The patients in the treatment group were administered with safflower yellow for injection 100 mg, and the patients in the control group were administered with ligustrazine hydrochloride injection 80 mg. The above two were added into 250 mL physiological saline for iv drip, once daily for 14 d. The patients in the two groups were recorded the clinical score and accepted transcranial Doppler (TCD) sonography to check the maximum blood flow velocity (Vsp) and mean blood flow velocity (Vmv) of cerebral anterior and media arteries before and after the treatment. At the same time, adverse reaction was observed in the treatment. Results After the treatment, the efficiency of treatment and control groups was 59.09% and 45.45% with significant difference (P < 0.05). TCD examination showed that Vsp and Vmv of cerebral media arteries in duty and non-duty area were increased more than those in the control group (P < 0.01, P < 0.05). There was no serious adverse reaction in the two groups. Conclusion Safflower yellow for injection could improve the clinical symptoms of patients by changing the blood flow in non-duty area, so that it could be chosen to use for the treatment in the cerebral infarction properly at the early recovery stage with the little adverse reaction.