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[摘要]
目的 观察鱼腥草滴眼液治疗急性卡他性结膜炎的临床疗效及安全性。方法 将100例急性卡他性结膜炎患者随机分为治疗组(50例)和对照组(50例),治疗组给予鱼腥草滴眼液,1滴/次,6次/d,对照组给予复方熊胆滴眼液,用法和用量同治疗组,两组均治疗7 d。治疗结束后,比较两组患者的疾病西医疗效和中医证候疗效,同时观察两组患者有无不良反应发生。结果 治疗组西医临床疗效的总有效率为97.92%,对照组为86.96%,两组比较差异有统计学意义(P<0.05)。在中医证候白睛红赤、胞睑红肿、眵多胶结、怕热畏光方面,治疗组优于对照组(P<0.05),目痒、流泪、口苦、尿黄证候两组差异无统计学意义(P>0.05)。结论 鱼腥草滴眼液治疗急性卡他性结膜炎疗效较好,临床应用安全。
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[Abstract]
Objective To evaluate the clinical efficiency and security of Yuxingcao Gutta, an eye drop consisted of Houttuyniae Herba, in the treatment of acute catarrhal conjunctivitis. Methods One hundred cases of acute catarrhal conjunctivitis were randomly divided into the treatment group (50 cases) and control group (50 cases), which were administered with Yuxingcao Gutta and Compound Xiongdan Gutta, an eye drop consisted of Ursi Fel, respectively. The course of treatment was 7 d and the dosage was one drop once, six times daily. The comprehensive curative effect and TCM syndrome curative effect of patients were observed after the treatment. At the same time, the adverse reaction was observed in the treatment. Results The efficacies in the treatment and control groups were 97.92% and 86.96%, respectively, with the significant difference between two groups (P < 0.05). TCM syndromes such as hyperemia of ocular conjunctiva, cell eyelid swelling, more ophthalmic gum (Chi) and cementation, and adversion to heat and photophobia in the treatment group were improved more significantly than those in the control group (P < 0.05). However, there was no statistic significance in the symptoms of itchy eyes, tears, bitter mouth, and yellow urine between the two groups (P > 0.05). Conclusion The clinical efficacy of Yuxingcao Gutta is better in the treatment of acute catarrhal conjunctivitis and the therapeutic effect is reliable and safe.
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