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[摘要]
目的 研究阔叶五层龙醋酸乙酯部位的化学成分。方法 采用硅胶柱色谱、葡聚糖凝胶柱色谱、ODS C18反相硅胶柱色谱相结合的方法进行分离纯化,根据化合物的理化性质和波谱数据鉴定已分得的化合物结构。结果 分离鉴定了7个化合物,分别为15-羟基-24-降甲基木栓烷-5-烯-1,3-二酮(1)、白桦脂酸(2)、2,3,11-三羟基乌苏-12-烯(3)、3,21-二羟基齐墩果-12-烯-28-酸甲酯(4)、magellanin(5)、胡萝卜苷(6)、D-甘油-D-半乳庚醇(7)。结论 化合物3~5、7为首次从翅子藤科分离得到,化合物1、2为首次从该植物中分离得到。
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[Abstract]
Objective To study the chemical constituents in the ethyl acetate extracting fraction from Salacia amplifolia. Methods The chemical constituents in the ethyl acetate fraction from S. amplifolia were isolated and purified by chromatography on silica gel, Sephadex LH-20, and ODS C18 reverse phase silica gel columns, and their chemical structures were identified by the physicochemical and spectroscopic data. Results Seven compounds were isolated and identified as 15-hydroxy-24-nor-friedel-5-ene-1,3-dione (1), pyracrenic acid (2), 2,3,11-trihydroxy-urs-12-ene (3), methyl-3,21-dihydroxy-olean-12-en-28-oate (4), magellanin (5), daucosterol (6), and D-glycero-D-galacto-heptitol (7). Conclusion Compounds 3—5 and 7 are isolated from the plants in Hippocrateaceae family for the first time and compounds 1 and 2 are isolated from this plant for the first time.
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