淫羊藿为我国传统中药，具有补肾阳、强筋骨、祛风湿的功效。淫羊藿中主要活性成分是以淫羊藿苷为代表的黄酮苷类化合物。近年来研究发现淫羊藿给药后发挥功效的物质基础主要为其活性成分的代谢产物。综述近年来国内外对淫羊藿中活性成分的代谢产物的研究方法及代谢产物研究进展，对进一步阐明淫羊藿药材的作用机制、研制新药具有直接指导意义。

Epimedii Herba is one of the traditional Chinese materia medica with the function of invigorating kidney, strengthening yang, and eliminating wind and dampness. Flavonoid glycosides of icariin as the representative, are the main active chemical components in Epimedii Herba. Recent studies have found that the material basis of these compounds may be their metabolites in vivo. The paper reviews the research progress in the metabolites of the active constituents in Epimedii Herba, which could provide the effective guidance for further understanding their mechanism and the development of the related drugs.

国家重大新药创制科技重大专项（2009ZX09102）