目的 观察香鳞毛蕨治疗难治性手足癣的临床疗效。方法 48例难治性手足癣患者的患手（足）浸泡于香鳞毛蕨水煮液或将药液涂于患处，每天1次，每次30 min，连续用药21 d，治疗前及治疗后第1周、第3周进行随访，同时进行临床评价和真菌学检查。结果 1周后，临床和真菌学治愈率分别为62.5%、56.3%，第3周后随访达91.7%、89.6%。结论 香鳞毛蕨治疗难治性手足癣效果显著，同时未见不良反应，值得临床推广使用。

Objective To observe the curative effect of Dryopteris fragrans on tinea pedis in clinic. Methods Forty-eight cases with stubborn tinea pedis were washed or soaked with D. fragrans once daily with 30 min for 21 d continuously. followed up before and after the treatment of week 1 and week 3, and evaluated the clinical effect and mycological examination at the same time. Results After week 1, the clinical effect and mycological cure rates were 62.5% and 56.3%, respectively, after week 3 were 91.7% and 89.6%. Conclusion D. fragrans showed the great treatment on stubborn tinea pedis with no side effects found, thus it is worth to promote the clinic use.