目的 观察酮咯酸氨丁三醇注射液用于无痛胃镜检查超前镇痛的临床效果。方法 选择2010年10月—2011年10月保定市急救中心无痛胃镜检查患者120例，随机分为观察组和对照组，观察组60例，术前30 min im酮咯酸氨丁三醇注射液60 mg；对照组60例，术前未用任何镇痛药。比较两组患者术前、术中、术后的血压（SBP）、心率（HR）、血氧饱和度（SPO2）、睫毛反射消失时间、术中不适情况、术毕清醒时间、丙泊酚总用量。结果 观察组术中SBP和HR的波动小于对照组；观察组丙泊酚总用药量及术中不适发生例数均小于对照组；观察组睫毛反射消失时间及清醒时间较对照组缩短，以上指标两组比较差异均有显著性（P＜0.05）。结论 酮咯酸氨丁三醇注射液用于无痛胃镜超前镇痛检查效果满意，可降低术中不适的发生率，减少丙泊酚用量，缩短苏醒时间。

Objective To observe the effects of ketorolac tromethamine injection used for preemptive analgesia of painless gastroscopy application. Methods One hundred and twenty patients in Baoding Emergency Center from October, 2010 to October, 2011 treated with painless gastroscopy were randomly divided into the observation and control groups, each group of 60 cases. Observation group was im injected ketorolac tromethamine injection 60 mg 30 min before operation; No any analgesics was used in the control group. The patients in the two groups were compared with preoperative, intraoperative, postoperative systemic blood pressure (SBP), heart rate (HR), oxygen saturation (SPO2), eyelash reflex lossing time, surgery discomfort, sober time of surgery, and propofol total amount during preoperation, intraoperation, and postoperation. Results SBP and HR fluctuations in the observation group were less than those in the control group; Propofol dosage and intraoperative discomfort cases in the observation group were less than the number of cases occurred in the control group; A set of eyelash reflex lossing time and sober time in the observation group was shorter than those in the control group. The above two indicators were statistical significance between the two groups (P＜0.05). Conclusion Ketorolac tromethamine injection used for preemptive analgesia of painless gastroscopy showed the satisfied treatments and could decrease the incidence of intraoperative discomfort, reduce the dosage of propofol, and shorten the sober time.