灵芝多糖是灵芝的主要活性成分之一，具有抗肿瘤、抗氧化、抗衰老和降血糖等生物活性，对近年来研究灵芝多糖的超声法、微波法、复合酶法等提取方法和径向流色谱、柱色谱联用等分离纯化方法，含量测定及其在抗肿瘤和抗氧化等方面的药理活性进行综述，为灵芝多糖的进一步开发利用提供依据。

Ganoderma lucidum polysaccharide is one of the major active components, which has many kinds of biological activities, such as anti-cancer, anti-oxidant, anti-aging, and reducing blood glucose. The recent studies on G. lucidum polysaccharide extraction methods, such as ultrasonic, microwave, and enzymatic methods; purification methods, such as radial flow chromatography and combined column chromatography; content determination; and pharmacological effects of anti-tumor and anti-oxidant are reviewed to provide the basic evidence for further utilization of G. lucidum polysaccharide.