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[摘要]
目的 建立枳术消食胶囊的质量控制方法。方法 采用薄层色谱法对制剂中白术、党参及槟榔进行定性鉴别,采用高效液相色谱法测定橙皮苷。结果 TLC鉴别色谱特征斑点明显。橙皮苷进样量0.115~2.300 μg与峰面积积分值的线性关系良好,平均回收率为99.32%,RSD为0.93%(n=6)。结论 所建立的薄层色谱和高效液相色谱法的专属性强,重复性好,可用于枳术消食胶囊的质量控制。
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[Abstract]
Objective To establish the quality control method for Zhizhu Xiaoshi Capsule. Methods The qualitative identification of Atractylodis Macrocephalae Rhizoma, Codonopsis Radix, and Arecae Semen was carried out by TLC, and the content of hesperidin was determined by HPLC. Results The TLC spots were quite clear. The linearity range was 0.115—2.300 μg for hesperidin by HPLC, and the average recovery was 99.32% for hesperidin with RSD of 0.93% (n=6). Conclusion The established TLC and HPLC methods are specific and reproducible and suitable for the quality control for Zhizhu Xiaoshi Capsule.
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