近几年来药物研发单位申请多晶体药物专利的数量在整个药品专利申请中所占比例不断上升。作为药物研发单位和生产企业的决策者和有关人员，特别是从事晶体药物研发的工作者非常有必要了解与晶体药物专利文件的撰写、药物专利的申请、审查和保护相关的知识。从新颖性、创造性、单一性方面介绍晶体药物专利申请的要求和注意事项，以及权利要求书、说明书的撰写技巧，供药物研发单位的相关人员参考。

In recent years, the number of the patents for crystalline drug from the R & D institutions has been rising rapidly compared with that of the other kinds of drug patents applying. The appliers, as a decision maker or a key working staff from R & D institutions or drug manufacturing enterprises, especially someone working on crystalline drug research, should know how to write, apply, examine， and protect the patents. This article introduces the requirements and notes for crystalline drug patent application, as well as the knowhow of writing claims and descriptions, from aspects of novelty, creativity, and unicity for reference.