研究龙血竭二氯甲烷提取部位中黄烷和高异黄烷类成分。方法 利用硅胶、聚酰胺柱色谱及反复重结晶等方法进行分离纯化，根据理化性质和波谱分析对分离得到的化合物进行结构鉴定。结果 分离得到6个化合物，分别鉴定为7-羟基-4′-甲氧基黄烷（1）、4′-羟基-7-甲氧基-8-甲基黄烷（2）、5,4′-二羟基-7-甲氧基-6-甲基黄烷（3）、7,4′-二羟基高异黄烷（4）、6,4′-二羟基-7-甲氧基高异黄烷（5）和10-羟基-11-甲氧基龙血酮（6）。结论 化合物6为首次从剑叶龙血树中分离得到，化合物2为首次从龙血竭中分离得到。

Objective To study the flavanes and homoisoflavanes from dichloromethane fraction in Chinese dragon’s blood. Methods The compounds were isolated by chromatography on silica gel, polyamide column and recrystallization and the chemical structures were identified on the basis of physico-chemical constants and spectral analyses. Results Six compounds were obtained and their structures were identified as 7-hydroxy-4′-methoxy flavane (1), 4′-hydroxy-7-methoxy-8-methylflavane (2), 5,4′-dihydroxy-7- methoxy-6-methyl flavane (3), 7,4′-dihydroxy-homoisoflavane(4), 6,4′-dihydroxy-7-methoxyhomoisoflavane (5), and 10-hydroxy- 11-methoxydracaenone (6). Conclusions Compound 6 is isolated from the plant for the first time and compound 2 is isolated from Chinese dragon’s blood for the first time.

国家自然科学基金资助项目（81173531）