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[摘要]
薏苡仁油及其有效成分薏苡仁酯具有直接的抗头颈部癌作用,也可通过提高机体的免疫功能间接杀伤癌细胞。其与放疗或化疗药联用,不仅可以对抗放、化疗抑制免疫功能等不良反应,提高患者的生存质量,甚至可以提高癌灶缓解率,减少肿瘤复发,延长生命,具有开发成抗头颈部癌新药的潜力。综述薏苡仁油抗头颈部癌的药理作用、作用机制及临床应用的研究进展。
[Key word]
[Abstract]
Coicis Semen oil and its active constituent coixenolide not only have the directly effect on kill cephalocervical cancer, but also have the indirect anti-cancer action by enhancement of immune function. In combination with chemotherapy or radiotherapy, it could reduce the adverse reactions of chemotherapy or radiotherapy, such as inhibition of immune function, increase living quality, enhance remission rate of cancer focus, decrease tumorous recurrence, and prolong life. Therefore, it has great potential for development into new drug against cephalocervical cancer. The research advances in the pharmacological effects, mechanism, and clinical application of Coicis Semen oil against cephalocervical cancer are reviewed in this paper.
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