近几十年来，阴、阳离子检测方法的发展非常迅速，检测方法有了较大的改进，同时离子种类得到很大的丰富。根据不同的药物分析目的可选择不同的检测方法，以取得最好的检测精度和灵敏度。简要地介绍了用于检测药物中常用的阴、阳离子的比浊法、比色法、滴定法、离子选择电极法、可见-紫外分光光度法、原子吸收分光光度法与色谱法等分析方法，并对今后的研究方向进行了展望。

Detection methods of negative and positive ion were rapidly developed for several decades. The kind of ion was plenty and the detection methods were improved. In order to obtain satisfied accuracy and sensitivity, we should choose a suitable method according to difference analysis objective. This article briefly summarized the application of detection methods to negative and positive ion in drugs, such as turbidimetry, colorimetry, titration, ion-selective electrode, ultraviolet-visible spectrophotometry, atomic absorption spectrophotometry, and chromatography, and so on. Finaly, the development trends of the technology have been prospected.