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[摘要]
我国是非小细胞肺癌高发国,非小细胞肺癌已经逐渐成为严重危害我国居民健康的疾病之一。目前针对非小细胞肺癌的治疗主要以化疗为主,但由于患者易对化疗药物产生耐药性,长期疗效一直不理想。目前国际上对非小细胞肺癌耐药相关生物标志物进行了很多研究,涉及到临床上多种不同类型的化疗药物,用来指导临床上开展的个体化治疗方案。针对目前临床上常见的几类化疗药物的耐药标志物进行综述,便于非小细胞肺癌患者个体化治疗的开展
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[Abstract]
Non-small cell lung cancer (NSCLC) is highly occurred in China, which has become the major cancer influencing human health. Nowadays the standard treatment for NSCLC is chemotherapy, however, chemoresistance was more and more frequently found in many patients, which to result in bad prognosis.So, lots of research on chemoresistant biomarkers in NSCLC has been launched. These biomarkers refer to several types of chemotherapeutics which could guide the therapeutic schedule in clinical medicine selections. In this article we focus on analyzing several chemoresistant biomarkers which may play an important role in implementation of individualized treatment for NSCLC.
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