观察股动脉溶栓治疗糖尿病足的临床疗效。方法 将40例糖尿病足患者随机分为治疗组和对照组，每组20例，治疗组患侧股动脉穿刺并滴注尿激酶（2.5×105 U）配合氢溴酸山莨菪碱（10 mg）溶栓，对照组静脉滴注前列腺素E1注射液（10 μg）。结果 治疗组糖尿病足的有效率95%，对照组的有效率80%，两组比较差异有显著性（P＜0.05）。足背动脉多普勒检查显示，治疗组治疗后血流速度改善显著优于对照组（P＜0.05）。结论 动脉内溶栓治疗糖尿病足具有操作简便、治疗时间短、见效快以及治疗费用低的特点，容易被老年患者接受，可以在老年病医院推广。

To investigate the clinical experience of diabetic foot (DF) by intra-femoral artery thrombolysis. Methods Forty patients with DF were randomly divided into two groups. The treatment group (20 cases) were puncturing femoral artery in the lesion side of lower-extremity to drip urokinase thrombolysis (2.5×105 U) combined with anisodamine hydrobromide (10 mg), the control group (20 cases) were injected PGE1 Injection by vein. Results The effective rate of DF was 95% in the treatment group and 80% in the control group, the difference between the two groups was significant (P<0.05). The Doppler of arteria dorsalis pedis showed that the improvement of blood flow rate in the treatment group was significantly outweigh that in the control group (P<0.05).