摘 要：目的 建立 HPLC 法测定荔枝核方中丹参素。方法 SinoChrom ODS-BP 色谱柱（200 mm×4.6 mm，5 μm），流动相为甲醇–1% 醋酸溶液（5∶95），柱温为室温，体积流量1.0 mL/min，检测波长280 nm。结果 丹参素在9.54～95.4 μg/mL 线性关系良好，r＝0.999 6；平均回收率为100.2%（RSD＝1.8%，n＝9）。结论 该方法操作简便，其他组分对测定无干扰，准确性和重现性好，可作为荔枝核方的质量控制方法。

Abstract: Objective To establish a method for determining the content of propanoid acid by HPLC．Methods The HPLC performed on a SinoChrom ODS-BP column（200 mm×4.6 mm，5 μm），mobile phase consisted of methanol-1% acetic acid（5∶95），column temperature was room temperature，flow rate was 1.0 mL/min，detection wavelength was 280 nm．Results The calibration curve was linear in the range of 9.54—95.4 μg/mL with good linearity（r＝0.999 6）．The average recovery was 100.2%（RSD＝1.8%，n＝9）．Conclusion The method is convenient，reliable，accurate and repeatable，and can be used in quality control of Semen Litchi Compound．