地骨皮具有凉血止血、清热退蒸、清泄肺热、清热滋阴、清热解毒的功效。其主要含生物碱类、有机酸类、蒽醌类、环肽类等成分，化学成分结构独特；药理活性也多样，具有降血压、调血脂、降血糖、解热、抗菌、抗病毒等活性，有重要应用价值。综述国内外对地骨皮的化学成分与药理作用的研究概况。

Lycium chinense Mill. has many functions such as clearing heat, stopping blee ding, nourishing Yin, and eliminating toxin. In it, there are many compounds with different structures, including alkaloids, organic acids, anthraquinone, and cyclopeptides. It has many pharmacological activities, including lowering blood pressure, serum lipid and glucose, removing heat, defending against bacteria and virus. Therefore, L. chinense Mill. is worthy of medicinal research and development. This paper summarizes the studies on chemical constituents and pharmacological activities of L. chinense Mill. in China and foreign countries.