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[摘要]
目的 建立舒天宁颗粒(天麻、栀子、川芎等)质量标准。方法 采用TLC法对方中天麻、栀子、川芎进行定性鉴别;采用HPLC法测定制剂中天麻素的量。结果 TLC法能特异性地鉴别天麻、栀子、川芎。天麻素在0.344~1.720 μg线性关系良好,r=0.999 9;加样回收率为97.65%,RSD为1.17%。结论 所建立的方法可准确地进行定性、定量检测,操作简便,专属性强,重现性好,可作为该颗粒的质量控制标准。
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[Abstract]
Objective To establish the quality standard of Shutianning Granules (Rhizoma Gastrodiae, Fructus Gardeniae, and Rhizoma Chuanxiong).Methods Rhizoma Gastrodiae, Fructus Gardeniae, and Rhizoma Chuanxiong were identified by TLC. Gastrodin was assayed by HPLC. Results Rhizoma Gastrodiae, Fructus Gardeniae, and Rhizoma Chuanxiong could be specifically identified by TLC. Gastrodin showed a good linear relationship at the range of 0.344-1.720 μg ( r=0.999 9). The average recovery of sample was 97.65%, RSD=1.17%.Conclusion The established method is simple, accurate, specific and reproducible, and suitable for the quality control of Shutianning Granules.
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