铁皮石斛是中国传统名贵中药，属补益药中的补阴药，具益胃生津、滋阴清热等功效，其质量标准的建立一直是热点研究问题。通过化学成分和药理活性这2个方面对铁皮石斛研究现状进行综述，并在此基础上基于中药质量标志物（Q-marker）的概念，分析其生源途径、传统功效、现代药理作用与化学成分之间的关系，对铁皮石斛的Q-marker进行预测分析，为建立和完善其质量标准提供依据。

Dendrobium officinale is a valuable traditional Chinese medicine. It is a yin tonic in the tonic medicine, which has the effects of nourishing the stomach and promoting hydration, nourishing yin and antipyretic, etc. The establishment of quality standards has been a hot research issue. In this paper, the chemical composition and pharmacological activities of D. officinale were summarized. Based on the concept of Chinese medicine Q-marker, the relationship between source pathways, chemical composition, and drug efficacy was analyzed, which can predict and analyze Q-marker of D. officinale, and provide a basis for establishing and improving its quality standards.

R285

省部共建亚热带森林培育国家重点实验室自主研究课题（ZY20180206）；浙江农林大学科研启动基金资助（2018FR003）；国家重点研发计划（2017YFC1702200）