[关键词]
[摘要]
目的 研究半红树植物玉蕊Barringtonia racemosa枝叶中的化学成分。方法 综合运用硅胶柱色谱、ODS柱色谱和Sephadex LH-20凝胶柱色谱以及制备型HPLC等方法进行系统分离和纯化,根据化合物的理化性质和波谱学数据,并通过与文献中报道的数据进行对照鉴定化合物的化学结构。结果 从半红树植物玉蕊枝叶的90%乙醇提取物中分离得到了17个化合物,分别鉴定为白杨素(1)、阿亚黄素(2)、芫花素(3)、鼠李柠檬素(4)、小麦黄素(5)、五桠果素(6)、5,3'-二羟基-7,4'-二甲氧基黄酮(7)、5,7,3',4'-四甲氧基黄酮(8)、5-羟基-6,7,8,3',4'-五甲氧基黄酮(9)、petasitolone(10)、sarmentol F(11)、dehydrovomifoliol(12)、blumenol A(13)、10-hydroxyaristolan-9-one(14)、麦珠子酸(15)、齐墩果内酯(16)和11,12-去氢熊果酸内酯(17)。结论 所有化合物均为首次从玉蕊属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents of the stems and leaves of semi-mangrove plant, Barringtonia racemosa. Methods The chemical constituents of B. racemosa were separated and purified by silica gel, ODS, Sephadex LH-20 gel column chromatographies and preparative HPLC. Their structures were identified by physicochemical properties, spectroscopic analysis, as well as comparisons with the data reported in literature. Results A total of 17 compounds were isolated from the 90% ethanol extract of the stems and leaves of B. racemosa, which were identified as chrysin (1), ayanin (2), genkwanin (3), rhamnocitrin (4), tricin (5), dillenetin (6), 5,3'-dihydroxy-7,4'-dimethoxyflavone (7), 5,7,3',4'-tetramethoxyflavone (8), 5-hydroxy-6,7,8,3',4'-pentamethoxy flavone (9), petasitolone (10), sarmentol F (11), dehydrovomifoliol (12), blumenol A (13), 10-hydroxyaristolan-9-one (14), alphitolic acid (15), oleanolic lactone (16), and 11,12-dehydroursolic acid lactone (17). Conclusion All compounds are isolated from the genus Barringtonia for the first time.
[中图分类号]
R284.1
[基金项目]
国家自然科学基金资助项目(21967008);国家自然科学基金资助项目(21662011);国家自然科学基金资助项目(31660097);海南省重点研发计划项目(ZDYF2019049);海口市重点研发计划项目(2017050);教育部创新团队项目(IRT-16R19)