三萜是许多药用植物的活性成分，目前已对其生物合成途径进行了大量研究并取得了重大进展。细胞色素P450（CYP450）主要参与三萜的后修饰过程，对三萜的多样性起着关键作用。目前，已从多种植物中克隆得到与三萜生物合成相关的CYP450基因。对参与三萜生物合成的CYP450的功能研究进行综述，为三萜生物合成途径的解析及CYP450的功能研究提供借鉴。

Triterpenoids are active constituents of many medicinal plants. The biosynthetic pathways of triterpenes have been fully studied and significant progress has been made. CYP450s are mainly involved in the post-modification process of triterpenoids biosynthesis, which plays a key role in the diversity of triterpenoids. Currently, a lot of CYP450s, which related to the biosynthesis of triterpenoids, have been cloned from many plants. In this paper, CYP450s involved in the biosynthesis of triterpenoids were reviewed, which provided a reference for the analysis of the biosynthetic pathway of triterpenoids and the functional study of CYP450s.

国家自然科学基金项目（81760690）；国家自然科学基金项目（81960693）；云南省科技厅科技计划项目（2018FB144）；云南省科学技术厅-云南中医药大学应用基础研究联合专项项目[2019FF002（-059）]；中央本级重大增减支项目：名贵中药资源可持续利用能力建设项目（2060302）