目的 验证蒸汽渗透技术分离细辛挥发油含油水体的可行性，进而将蒸汽渗透技术应用于更多中药挥发油含油水体的分离。方法 以聚二甲基硅氧烷/聚偏氟乙烯（PDMS/PVDF）复合平板膜和PVDF平板膜为膜材料，采用蒸汽渗透技术分离细辛挥发油含油水体，计算2种膜的透油率，同时通过气相色谱-质谱（GC-MS）联用技术分析比较过膜前后挥发油成分种类和含量的变化。结果 以PVDF膜为膜材料进行蒸汽渗透实验时，其挥发油的透油率明显高于PDMS/PVDF膜，GC-MS定性分析结果显示，2种膜的渗透液中挥发油的成分与传统水蒸气蒸馏法得到的挥发油中的成分基本一致，以双内标法对其中的α-蒎烯、β-蒎烯、3,5-二甲氧基甲苯和甲基丁香酚4种成分进行含量测定，结果发现PVDF膜渗透液中各成分的含量明显高于PDMS/PVDF膜渗透液。结论 蒸汽渗透膜技术分离细辛挥发油含油水体是可行的，且与PDMS/PVDF膜相比，PVDF膜更适用于分离细辛挥发油含油水体。

Objective To verify the feasibility of vapor-permeable membrane technology for the separation of water bodies containing essential oil of Asari Radix et Rhizoma (ARR) essential oil, and then to apply vapor permeate technology to the separation of more essential oils of traditional Chinese medicine. Methods The polydimethylsiloxane/polyvinylidene fluoride (PDMS/PVDF) composite flat membrane and polyvinylidene fluoride (PVDF) flat membrane were collected as the membrane material. The oil-bearing water body of ARR volatile oil was separated by vapor permeate technology, and the oil penetration rate of two kinds of membranes was calculated. At the same time, the changes of the composition and content of the essential oil before and after the membrane were analyzed by gas chromatography-mass spectrometry (GC-MS). Results The results showed that the essential oil penetration rate was significantly higher than that of PDMS/PVDF membrane when PVDF membrane was used as membrane material. GC-MS qualitative analysis results showed that the composition of the essential oil in the penetrants of the two membranes was basically the same as that of the essential oil obtained by the traditional steam distillation method. The content of α-pinene, β-pinene, 3,5-dimethoxytoluene, and methyl eugenol were determined by double internal standard method. The results showed that the content of each component in the PVDF membrane permeation was significantly higher than that of the PDMS/PVDF membrane permeation solution. Conclusion It is feasible to separate the oil containing water from the essential oil of ARR by vapor permeation membrane technology. Compared with the PDMS/PVDF membrane, the PVDF membrane is more suitable for separating the oil containing water of the essential oil of ARR.

国家自然科学基金面上项目（81673610）；国家自然科学基金面上项目（81773919）；国家自然科学基金面上项目（81773912）；国家“十二五”重大新药创制专项（2011ZX09401-308-037）；中国工程院重点咨询研究项目（2017-XZ-08）；江苏省科技厅重点研发计划——社会发展面上项目（BE2016754）；江苏省六大人才高峰项目（2014-YY-014）；江苏省“青蓝工程”资助；江苏省优势学科资助； 2018年江苏省研究生科研创新计划（KYCX18_1632）