“绿色制造”是一个综合考虑环境影响和资源消耗的现代制造模式，其宗旨是对环境负面影响最小，资源利用率最高，并使企业经济效益与社会效益协调优化。《中医药发展战略规划纲要（2016-2030年）》明确将建立中药绿色制造体系制定为重点任务，在中药制药行业大力推广绿色制造理念与技术迫在眉睫。依据绿色制造的基本理念，结合科技实践，系统论述“中药绿色制造”的概念、目标与重点研究内容，以期为构建中药绿色制造理论与技术体系提供借鉴。主要论点包括中药绿色制造是一项系统工程；中药绿色制造理论与技术体系中的“资源”定位具有国家战略意义；具有各种活性成分的化学组合体是中药资源的核心价值所在；中药制造绿色工艺技术的核心是分离；产业生态学及其实践产物工业生态园是中药绿色制造的根本出路等。

“Green manufacturing” is a modern manufacturing model that comprehensively considers environmental impact and resource consumption. Its purpose is to minimize the negative impact on the environment and maximize resource utilization, and to coordinate and optimize the economic and social benefits of the enterprise. The Outline for Strategic Development of Chinese Medicine (2016—2030) clearly defines to establish a green manufacturing system for Chinese materia medica (CMM) as a key task, and it is imminent to vigorously promote “green manufacturing” concepts and technologies in the pharmaceutical industry of CMM. Based on the basic concept of “green manufacturing” and the scientific practice of the author’s research group for many years, this article systematically discusses the concept, goals and key research content of green manufacturing of CMM in order to provide reference for the construction of “the theory and technology system of green manufacturing of traditional Chinese medicine”. The main arguments include that green manufacturing of CMM is a systematic project, the positioning of resources in the theory and technology system of green manufacturing of CMM has a national strategic significance; A chemical combination with various active ingredients is the core value of CMM resources; Separation is the core of green manufacturing process technology, and industrial ecology with its practical product “industrial ecological park” is the fundamental way out of green manufacturing of CMM.

国家自然科学基金资助项目（81274096）；国家自然科学基金资助项目（81303230）；国家自然科学基金资助项目（81673610）；国家自然科学基金面上项目（81773912）；国家自然科学基金面上项目（81873015）；2017中国工程院咨询项目（2017-XZ-08）；江苏省中药资源产业化过程协同创新中心分离平台建设项目（ZDXM-1-6，ZDXM-1-8）