[关键词]
[摘要]
黄酮类化合物具有多方面的生理和药理活性,而离子液体因其独特的性质在天然产物黄酮类成分的提取中应用越来越多。综述了目前天然产物中黄酮类成分的提取方法,以及离子液体特别是咪唑类离子液体的阴阳离子类型、碳链长度、键合作用等对天然黄酮类化合物提取的影响规律,提出了应用于黄酮类化合物离子液体萃取剂选择的建议,并指出离子液体的绿色回收和可食用型离子液体的开发是未来的发展方向,为离子液体在天然黄酮类成分开发中的基础研究和工业应用奠定基础。
[Key word]
[Abstract]
Flavonoids have many physiological and pharmacological activities. Ionic liquids are increasingly used in the extraction of flavonoids from natural products due to their unique properties. In this paper, various extraction methods of natural flavonoids were reviewed and summarized. The effects of anion and cation type, length of carbon chain, and bond cooperation on the extraction of natural flavonoids in ionic liquids, especially imidazole type ionic liquids, were also reviewed. Suggestions on selection of extractant for ionic liquid extraction of flavonoids were given. The advice of the green recovery of ionic liquids and the development of edible ionic liquids for the future direction of development were suggested. This study will lay the foundation for the basic research and industrial application of ionic liquids in the extraction of natural flavonoids.
[中图分类号]
R284;O6-332
[基金项目]
国家自然科学基金青年科学基金项目(21406015);北京市教委科研计划项目(KM201510017006);北京石油化工学院校内学科平台建设项目(2018XK002);北京市大兴区科技发展计划项目(KT201806402);平顶山学院高层次人才科研启动经费资助项目(PXY-BSQD-2015007);河南省科技厅项目(172102310210)