[关键词]
[摘要]
目的 研究蒙药玉簪Hosta plantaginea花的化学成分。方法 通过溶剂法与多种现代色谱技术对蒙药玉簪花的化学成分进行提取和系统分离,应用理化鉴别及现代波谱分析技术鉴定化合物的结构。结果 从蒙药玉簪花中分离得到12个化合物,分别鉴定为腺嘌呤核苷(1)、山柰酚-3-O-β-D-吡喃葡萄糖基(1→2)-β-D-吡喃葡萄糖基-7-O-β-D-吡喃葡萄糖苷(2)、山柰酚-3-O-α-L-吡喃鼠李糖基-(1→6)-β-D-吡喃葡萄糖基-7-O-β-D-吡喃葡萄糖苷(3)、山柰酚-3-O-{β-D-吡喃葡萄糖基(1→2)-[α-L-吡喃鼠李糖基-(1→6)]-β-D-吡喃葡萄糖基}-7-O-β-D-吡喃葡萄糖苷(4)、山柰酚-3-O-β-D-吡喃葡萄糖苷(5)、羟基苯甲酸(6)、对羟基苯丙酸(7)、山柰酚-3-O-{β-D-吡喃葡萄糖基(1→3)-[α-L-吡喃鼠李糖基(1→6)]-β-D-吡喃葡萄糖苷}(8)、山柰酚-3-O-{β-D-葡萄糖基-(1→2)-[α-L-鼠李糖基(1→6)]-β-D-葡萄糖苷}(9)、山柰酚-3,7-二-O-β-D-吡喃葡萄糖苷(10)、7-甲氧基-山柰酚-3-O-β-D-吡喃葡萄糖基-(1→2)-β-D-吡喃葡萄糖苷(11)、熊果酸(12)。结论 化合物2~4、9为首次从该种植物中分离得到,化合物1、5~8、10~12为首次从该属植物中分离得到。
[Key word]
[Abstract]
Objective To investigate the chemical constituents of Mongolia medicine Hostae Flos (Flowers of Hosta plantaginea). Methods Chemical constituents of Mongolia medicine Hostae Flos were isolated and purified by Solvent method and chromatographic method. Their structures were elucidated on the basis of physio-chemical identification and spectral analysis. Results Twelve compounds were obtained from Hostae Flos. Their structures were identified as adenosine (1), kaempferol 3-O-β-D-glucopyranosyl (1→2)-β-D-glucopyranosyl-7-O-β-D-glucopyranoside (2), kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-7-O-β-D-glucopyranoside (3), kaempferol 3-O-{β-D-glucopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranosyl}-7-O-β-D-glucopyranoside (4), kaempferol 3-O-β-D-glucopyranoside (5), hydroxybenzoic acid (6), hydroxyphenyl propionate (7), kaempferol 3-O-{β-D-glucopyranosyl (1→3)-[α-L-rhamnopyranosy-(1→6)]-β-D-glucopyranoside} (8), kaempferol 3-O-{β-D-glucopyranosyl (1→2)-[α-L-rhamnopyranosyl (1→6)]-β-D-glucopyranoside}(9), kaempfero-3,7-di-O-β-D-glucopyranoside (10), 7-methoxyl-kaempferol-3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside (11), and ursolic acid (12). Conclusion Compounds 2-4 and 9 are obtained from H. plamtaginea for the first time. Compounds 1, 5-8, 10-12 are isolated from the genus Hosta for the first time.
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[基金项目]
国家自然科学基金资助项目(81060256);内蒙古自然科学基金项目(2009BS1203);内蒙古自治区应用技术与开发资金项目(20100501);内蒙古自治区草原英才工程项目(内组通字[2014]27号);内蒙古自治区草原英才滚动支持项目(内组通字[2017]19号)