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[摘要]
目的 研究多花山竹子Garcinia multiflora果实化学成分。方法 采用正、反相硅胶柱色谱及高效液相色谱等多种技术进行分离纯化,并通过谱学数据鉴定化合物结构。结果 从多花山竹子果实乙醇提取物中分离得到了6个化合物,分别鉴定为多花山竹子酮素甲(1)、sargaol(2)、δ-生育三烯酚(3)、木犀草素(4)、1,3,6,7-四羟基(口山)酮(5)、对苯二甲酸二(2-乙基)己酯(6)。结论 化合物1为新的类金刚烷型间苯三酚类化合物,化合物2、3、6均为首次从该植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical constituents of the fruits of Garcinia multiflora.Methods The constituents were isolated and purified by silica gel column chromatography and semipreparative HPLC, and their structures were elucidated by means of spectroscopic analyses.Results Six compounds were obtained and identified as multiflorone A (1), sargaol (2), δ-tocotrienol (3), luteolin (4), 1,3,6,7-tetrahydroxyxanthone (5), terephthalic acid bis (2-ethyl-hexyl) ester (6).Conclusion Compound 1 is a new homoadamantyl type phloroglucinol, and compounds 2, 3 and 6 are isolated from this plant for the first time.
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[基金项目]
国家自然科学基金资助项目(31370379);国家重大新药创制科技重大专项(2017Z09301060);中央高校基本科研业务费资助项目(CZP18004)